Changes

**Expensive

**Expensive

*Fecal microbiota transplant (83-94% success rate for recurrent COL).  

*Fecal microbiota transplant (83-94% success rate for recurrent COL).  

**Fecal microbiota transplantation restores gut microbiota diversity, with the

**Fecal microbiota transplantation restores gut microbiota diversity, with the instillation of donor stool into the gastrointestinal tract of an infected patient.

instillation of donor stool into the gastrointestinal tract of an infected patient

**This procedure has had good clinical response without reports of adverse events, for refractory or recurrent CDI.  

**This procedure has had good clinical response without reports of adverse events, for refractory or recurrent CDI.  

**The first systematic review was published in 2011 and

**The first systematic review was published in 2011 and included 317 patients with recurrent CDI treated with fecal microbiota transplantation via enema, nasojejunal-tube/gastroscope or colonoscopy.  

included 317 patients with recurrent CDI treated with fecal microbiota transplantation via enema, nasojejunal-tube/gastroscope or colonoscopy.  

**Clinical resolution occurred in 92% of patients (89% after a single treatment), without serious adverse effects.

**Clinical resolution occurred in 92% of patients (89% after a single treatment), without serious adverse effects.

**A recent review of 536 patients reported a 27% clinical response rate.

**A recent review of 536 patients reported a 27% clinical response rate.