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659 bytes added ,  20:50, 31 January 2023
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{| class="wikitable"
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|+ Commonly Used Opioids
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|-
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! Opioid !! Dose !! Onset !! Duration !! Elimination !! Unique effects/indications
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|-
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| Fentanyl || 1-20 ug/kg || 4-6 min || 15-30 min || Hepatic/Renal || Example
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|-
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| Sufentanyl || 0.3-1 ug/kg || 2-4 min || 5-15 min || Hepatic/Renal || Example
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|-
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| Remifentanyl || 0.1-0.3 ug/kg || 1-2 min || 2-5 min || Plasma esterases || Example
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|-
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| Alfentanyl || 15-50 ug/kg || Example || Example || Hepatic/Renal || Example
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|-
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| Morphine sulfate || 25-75 mg || 10-30 min || 2-5 hrs || Example || Can cause histamine release
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|-
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| Meperidine || Example || 10-30 min || 2-5 hrs || Example || Used for post-op shivering
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|}
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* Don’t combine [[benzodiazepines]] and opioids. If you need to reverse, use [[flumazenil]].  
 
* Don’t combine [[benzodiazepines]] and opioids. If you need to reverse, use [[flumazenil]].  
 
* Central loci of opioid action (descending inhibitory pain pathways)
 
* Central loci of opioid action (descending inhibitory pain pathways)

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