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Diagnosis and Treatment or C.ostradaul der
Diagnosis and Treatment of C.difficil per
Natasha Bagdasarian et al.
Natasha Bagdasarian et al.
Published in JAMA 2019.
Published in JAMA 2019.
Systematic review of 116 included studies between 1978 and 2014.
Systematic review of 116 included studies between 1978 and 2014.
DIAGNOSIS
==DIAGNOSIS==
Laboratory testing cannot distinguish between asymptomatic colonization and
Laboratory testing cannot distinguish between asymptomatic colonization and
¿Eyed frat' cuitisten a forfindsfficile. The best test performance characteristics
¿Eyed frat' cuitisten a forfindsfficile. The best test performance characteristics
-Highest NPV (99.8%) GDH EIA + NAAT
-Highest NPV (99.8%) GDH EIA + NAAT
---Highest PPV (93.5%) Toxin EIA 1 + NAAT
---Highest PPV (93.5%) Toxin EIA 1 + NAAT
TREATMENT
==TREATMENT==
-First line treatment
-First line treatment
-PO Vancomycin (78.5% success rate, 25,3% recurrence rate)
-PO Vancomycin (78.5% success rate, 25,3% recurrence rate)