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* Reversible chemical/optical/electromagnetic knockdown/inhibition/interference of pain nuclei/DRG/dorsal column/STT activity in rodents/primates
* Reversible chemical/optical/electromagnetic knockdown/inhibition/interference of pain nuclei/DRG/dorsal column/STT activity in rodents/primates
* Fentanyl patch instead of remifentanil infusion? What other anesthetics could you deliver via patch? Could you do a patch induction for Peds? There is no remifentanil or sufentanil patch.
* Fentanyl patch instead of remifentanil infusion? What other anesthetics could you deliver via patch? Could you do a patch induction for Peds? There is no remifentanil or sufentanil patch.
* What is the MoA of APAP?
* Find a better trigger for transfusion threshold. Hgb mass loss vs. qBL vs. EBL are all various ways of getting at how much blood was lost, but why do we even care? Is that even useful information? How much Hgb do you need? Is Hgb concentration even the right thing to measure for a transfusion threshold? What you really want to know is whether they lost so much blood that they require a transfusion to provide adequate tissue oxygenation. Are there other reasons to care? Is there an early marker of tissue hypoxia that would make a better laboratory marker for determining need for blood transfusion?
* Find a better trigger for transfusion threshold. Hgb mass loss vs. qBL vs. EBL are all various ways of getting at how much blood was lost, but why do we even care? Is that even useful information? How much Hgb do you need? Is Hgb concentration even the right thing to measure for a transfusion threshold? What you really want to know is whether they lost so much blood that they require a transfusion to provide adequate tissue oxygenation. Are there other reasons to care? Is there an early marker of tissue hypoxia that would make a better laboratory marker for determining need for blood transfusion?
** Hgb mass loss (HML) takes the concentration of Hgb in the suction canister (including irrigation) and multiplies it by the volume to yield the total hemoglobin mass in the canister. This could then be divided by the starting Hgb concentration to determine the volume of blood lost.
** Hgb mass loss (HML) takes the concentration of Hgb in the suction canister (including irrigation) and multiplies it by the volume to yield the total hemoglobin mass in the canister. This could then be divided by the starting Hgb concentration to determine the volume of blood lost.