Changes

==Ankylosing Spondylitis==

==Ankylosing Spondylitis==

*H&P: Chronic low back pain in young men that is worse in the morning and improves throughout the day, associated with HLA-B27 serotype

*H&P: Chronic low back pain in young men that is worse in the morning and improves throughout the day, associated with HLA-B27 serotype

*Dx: Elevated CRP, X-rays of SI joint (earliest radiographic finding), "bamboo spine", squaring of lumbar vertebrae, kyphosis, ascending fusion of spinal column. Associated with apical pulmonary fibrosis (ILD), uveitis, aortitis, psoriasis, IBD

*Dx: X-rays of SI joint (earliest radiographic finding), "bamboo spine", squaring of lumbar vertebrae, kyphosis, ascending fusion of spinal column. Associated with apical pulmonary fibrosis (ILD), uveitis, aortitis, psoriasis, IBD

*Tx: NSAIDs and exercise are first line. Second line is anti-TNF

*Tx: NSAIDs and exercise are first line. Second line is anti-TNF