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→Pemphigus Vulgaris
=Pemphigus Vulgaris=
=Pemphigus Vulgaris=
*H&P: Autoimmune disease targeting desmoglein. Flaccid bullae and erosions, oral lesions precede skin lesions. + Nikolsky sign.
*H&P: Autoimmune disease targeting desmoglein. Flaccid bullae and erosions, oral lesions precede skin lesions. + Nikolsky sign.
*Dx: Skin biopsy. "Tombstoning" on immunofluorescence.
*Dx: Skin biopsy. "Tombstoning" on immunofluorescence. Differential includes EM, SJS, TEN
*Tx: Corticosteroids and immunosuppressives. Can affect the esophagus.
*Tx: Corticosteroids and immunosuppressives. Can affect the esophagus.
=Bullous Pemphigoid=
=Bullous Pemphigoid=