Difference between revisions of "Nervous System Overview"

Revision as of 23:28, 27 January 2023

CENTRAL
- Brain
  - Forebrain
  - Midbrain
  - Hindbrain
- Spinal Cord
  - Cervical
  - Thoracic
  - Lumbar
  - Sacral
PERIPHERAL
- Somatic
  - Efferent/Motor: primary motor cortex glutamatergic UMNs > corticospinal tract > anterior horn cholinergic alpha motor neurons (LMNs) > ventral roots > peripheral nerves > nAChRs on skeletal muscles
  - Afferent/Sensory: peripheral sensory receptors > peripheral nerves > dorsal roots > DCML/spinothalamic
- Autonomic
  - Sympathetic
    - Efferent: lateral horn cholinergic preganglionic neurons > ventral roots > white ramus communicans > nAChRs on postganglionic noradrenergic neurons in the paravertebral sympathetic chain or prevertebral ganglia > gray ramus communicans > peripheral nerves > adrenergic receptors (α1/α2, β1/β2) on target organs
    - Afferent: ...
  - Parasympathetic
    - Efferent: cholinergic preganglionic neurons > craniosacral outflow from CN III/VII/IX, CN X, and S2-S4 > nAChRs on postganglionic cholinergic neurons in the parasympathetic/peripheral ganglia on/near target organs > (trigeminal nerve branches for efferents from CN III/VII/IX) > mAChRs on target organs
    - Afferent: ...
- Enteric

@@ Line 15: / Line 15: @@
 **'''Autonomic'''
 ***Sympathetic
-****Efferent: ''lateral horn [[cholinergic]] preganglionic neurons'' > ventral roots > white ramus communicans > paravertebral sympathetic chain or prevertebral ganglia containing postganglionic [[noradrenergic]] neurons > gray ramus communicans > peripheral nerves > [[adrenergic]] receptors (α1/α2, β1/β2) on target organs
+****Efferent: ''lateral horn [[cholinergic]] preganglionic neurons'' > ventral roots > white ramus communicans > [[nAChRs]] on postganglionic [[noradrenergic]] neurons in the paravertebral sympathetic chain or prevertebral ganglia > gray ramus communicans > peripheral nerves > [[adrenergic]] receptors (α1/α2, β1/β2) on target organs
 ****Afferent: ...
 ***Parasympathetic
-****Efferent: ''[[cholinergic]] preganglionic neurons'' > craniosacral outflow from CN III/VII/IX, CN X, and S2-S4 > [[nAChRs]] of parasympathetic/peripheral ganglia containing postganglionic [[cholinergic]] neurons on/near target organs > (trigeminal nerve branches for efferents from CN III/VII/IX) > [[mAChRs]] on target organs
+****Efferent: ''[[cholinergic]] preganglionic neurons'' > craniosacral outflow from CN III/VII/IX, CN X, and S2-S4 > [[nAChRs]] on postganglionic [[cholinergic]] neurons in the parasympathetic/peripheral ganglia on/near target organs > (trigeminal nerve branches for efferents from CN III/VII/IX) > [[mAChRs]] on target organs
 ****Afferent: ...
 **'''Enteric'''