Difference between revisions of "Opioids"
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* Don’t combine [[benzodiazepines]] and opioids. If you need to reverse, use [[flumazenil]]. | * Don’t combine [[benzodiazepines]] and opioids. If you need to reverse, use [[flumazenil]]. | ||
| + | * Central loci of opioid action (descending inhibitory pain pathways) | ||
| + | ** PAG | ||
| + | ** Nucleus Raphe magnus | ||
| + | ** Rostral ventromedial medulla | ||
=Short-Acting= | =Short-Acting= | ||
* Oxycodone, Hydromorphone, Morphine | * Oxycodone, Hydromorphone, Morphine | ||
Revision as of 19:51, 29 August 2022
- Don’t combine benzodiazepines and opioids. If you need to reverse, use flumazenil.
- Central loci of opioid action (descending inhibitory pain pathways)
- PAG
- Nucleus Raphe magnus
- Rostral ventromedial medulla
Short-Acting
- Oxycodone, Hydromorphone, Morphine
- Morphine can cause rash/pruritis
Long-Acting
- Oxycodone ER = OxyContin
- Methadone
- Fentanyl is really only used intra-op or in palliative care.