Difference between revisions of "OHSU Research Ideas"

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* Dale Hodges
 
* Dale Hodges
 
* Liz Moss
 
* Liz Moss
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=SCD effects on hemodynamics=
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*Moady et al IMAJ 2019: In healthy volunteers, pneumatic sleeve (PS) compression devices applied to both legs from toe to thigh an inflated to a pressure of 50 or 80 mmHg increased CO, decrease SVR, and have no effect on HR (see ref 16). In CHF patients, the same method does not exacerbate symptoms and increases CO via an increase in SV, decreases SVR, and has no effect on HR (see ref 17). This study however showed that HFrEF patients who were medically optimized had '''no change in any hemodynamic parameter after 60 minutes of PS application''', and that they tolerated it well without any increase in their BNP.

Revision as of 20:48, 14 July 2023

  • Wearable clinical alarms (2 relevant results, 1 highly relevant result)
  • VR for IV placement peds (6 articles spanning 2020-2022, 5 RCTs, and a systematic-review and meta-analysis)
  • Does change in PPV/CO after SCD activation predict fluid responsiveness and how does it compare to SLR?
  • EEG/MEP/SSEP patterns in monkeys/humans taking THC vs controls
  • Reversible chemical/optical/electromagnetic knockdown/inhibition/interference of pain nuclei/DRG/dorsal column/STT activity in rodents/primates
  • NIBP monitoring from head/neck
  • Better way of determining fluid status
  • EPIC timeline builder

Resources

  • Schnell lab
  • Leimer/Lo lab (THC, NHPs)
  • Saugstad lab (EVs)
  • Schennings (Gas vs. TIVA risk of post-op delirium, assessed via CAM)
  • Schulman (interrogate ICDs for EMI after surgery)
  • Austin Peters
  • Selva Balkan
  • Dale Hodges
  • Liz Moss

SCD effects on hemodynamics

  • Moady et al IMAJ 2019: In healthy volunteers, pneumatic sleeve (PS) compression devices applied to both legs from toe to thigh an inflated to a pressure of 50 or 80 mmHg increased CO, decrease SVR, and have no effect on HR (see ref 16). In CHF patients, the same method does not exacerbate symptoms and increases CO via an increase in SV, decreases SVR, and has no effect on HR (see ref 17). This study however showed that HFrEF patients who were medically optimized had no change in any hemodynamic parameter after 60 minutes of PS application, and that they tolerated it well without any increase in their BNP.