Difference between revisions of "Sepsis"

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==Diagnosis==
 
==Diagnosis==
 
* SIRS, severe sepsis, and septic shock are outdated concepts from the 1990s.
 
* SIRS, severe sepsis, and septic shock are outdated concepts from the 1990s.
* Most recent definitions are from [[2016 Surviving Sepsis | https://oce.ovid.com/article/00005407-201602230-00023]]
+
* Most recent definitions are from [[https://oce.ovid.com/article/00005407-201602230-00023|2016 Surviving Sepsis]]
** Life threatening organ dysfunction due to systemic infection
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** "Life-threatening organ dysfunction caused by a dysregulated host response to infection"
 
** qSOFA (outpatient) or SOFA (ICU) score are screening tools for organ dysfunction, NOT for sepsis
 
** qSOFA (outpatient) or SOFA (ICU) score are screening tools for organ dysfunction, NOT for sepsis
 
** [[Shock]]: Persistent hypotension, not responsive to fluids, requiring pressors to keep [[MAP]] > 65, and lactate > 2
 
** [[Shock]]: Persistent hypotension, not responsive to fluids, requiring pressors to keep [[MAP]] > 65, and lactate > 2

Latest revision as of 17:41, 5 October 2022

Diagnosis

  • SIRS, severe sepsis, and septic shock are outdated concepts from the 1990s.
  • Most recent definitions are from [Surviving Sepsis]
    • "Life-threatening organ dysfunction caused by a dysregulated host response to infection"
    • qSOFA (outpatient) or SOFA (ICU) score are screening tools for organ dysfunction, NOT for sepsis
    • Shock: Persistent hypotension, not responsive to fluids, requiring pressors to keep MAP > 65, and lactate > 2