Asthma

Obstructive lung disease characterized by episodic wheezing, dyspnea, and cough, that is reversible with bronchodilators. Decreased FEV1, FEV1/FVC, increased TLC, RV, normal DLCO. FEV1 improved >12% and >200 mL with bronchodilators. Typically diagnosed in early childhood to adolescence. Risk factors include childhood eczema, cigarette smoke exposure.

• ABPA is diagnosed with eosinophilia, positive aspergillum skin testing, and elevated serum IgE.
• ABPA is treated with systemic glucocorticoids and itraconazole or voriconazole. Do not use fluconazole.