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− | =Hypertension= | + | =Essential Hypertension= |
− | * Primary/Essential Hypertension | + | * Primary/Essential Hypertension (95% of cases) |
− | ** Dx: Rule out secondary causes, BP > 130/90 on two separate occasions. | + | ** Dx: Rule out secondary causes, BP > 130/90 on three separate occasions. |
− | ** DDx: Secondary HTN--RAS, Hypo/Hyper(para)thyroidism, Conn syndrome, Cushing's syndrome, Pheochromocytoma | + | ** DDx: Secondary HTN (5% of cases; suspect if patient very young, very old, very high BP, or refractory to treatment) |
− | ** Tx: Can start with 1 or 2 agents depending on severity. First line: ACEI/ARB (good for kidney protection), (Non)Dihydropyridine CCB, Beta Blockers (cardiac selective, non-selective), Thiazide/Non-Thiazide Type Diuretics (second line) | + | *** Endocrine: [[Conn syndrome]] (most common), [[Cushing's syndrome]], [[Pheochromocytoma]], [[Hyperthyroidism]], [[Hyperparathyroidism]] |
| + | *** Renal: bilateral [[RAS]], [[PKD]], [[CKD]] |
| + | *** Other: [[Cocaine]], [[OSA]], [[OCPs]], [[Coarctation]] |
| + | ** Tx: For SBP 121-139 or DBP 81-89, start with 8-12 weeks lifestyle modifications and reassess. Can start with 1 or 2 agents depending on severity. First line: ACEI/ARB (good for kidney protection), Dihydropyridine CCB > non-dihydropyridine CCB, Beta Blockers (cardiac selective (MAN BABES) > non-selective), Thiazide-Like Diuretics > Thiazide-Type Diuretics. Special populations: CHF (avoid CCBs, use beta blockers), CKD (use ACEI/ARB), Pregnancy (hydralazine, labetalol, nicardipine, methyldopa), post-MI (use beta blockers + ACEI/ARB), Blacks (CCB + thiazide-like diuretic) |
| * Hypertensive Urgency BP > 180 | | * Hypertensive Urgency BP > 180 |
| * Hypertensive Emergency BP > 180 + symptoms | | * Hypertensive Emergency BP > 180 + symptoms |