1,022
edits
Changes
Jump to navigation
Jump to search
Line 114:
Line 114: − +
→PSC
==PSC==
==PSC==
*H&P: '''Intra and extra hepatic''' bile duct '''fibrosis'''; Age 30-40; M>F; associated with IBD (UC>Crohn's); asymptomatic or presenting with fatigue, pruritic, RUQ pain
*H&P: '''Intra and extra hepatic''' bile duct '''fibrosis'''; Age 30-40; M>F; associated with IBD (UC>Crohn's); asymptomatic or presenting with fatigue, pruritic, RUQ pain
*Dx: Elevated ALK + bili; '''ANA, anti smooth muscle, and anti pANCA''' antibodies.
*Dx: Elevated ALK + bili; '''ANA, anti smooth muscle, and anti pANCA''' antibodies; bile duct dilation on imaging
*Tx: Ursodeoxycholic acid, cholestyramine, fat-soluble vitamins; transplant '''frequently''' required
*Tx: Ursodeoxycholic acid, cholestyramine, fat-soluble vitamins; transplant '''frequently''' required