Difference between revisions of "NSAIDs"

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* e.g. Ibuprofen, Naproxen, Ketorolac
 
* e.g. Ibuprofen, Naproxen, Ketorolac
* Renal excretion. Acts on COX 1/2. Inhibits renal production of prostaglandins.  
+
* Renally excreted. Acts on COX 1/2. Inhibits renal production of prostaglandins.  
* Safe for short term use in patients with stage 1-2 CKD. Risk of causing AKI is same as in general population. No evidence that it will increase risk of progression.
+
* Safe for short term use in patients with stage 1-2 [[CKD]]. Risk of causing [[AKI]] is same as in general population. No evidence that it will increase risk of progression.
 
* Schedule NSAIDs, if they are only PRNs they likely won’t happen.
 
* Schedule NSAIDs, if they are only PRNs they likely won’t happen.
 +
* Topical = Diclofenac gel (Voltaren).

Latest revision as of 13:48, 2 August 2022

  • e.g. Ibuprofen, Naproxen, Ketorolac
  • Renally excreted. Acts on COX 1/2. Inhibits renal production of prostaglandins.
  • Safe for short term use in patients with stage 1-2 CKD. Risk of causing AKI is same as in general population. No evidence that it will increase risk of progression.
  • Schedule NSAIDs, if they are only PRNs they likely won’t happen.
  • Topical = Diclofenac gel (Voltaren).