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→Myasthenia Gravis
*H&P: Autoantibodies against AChR, presents with muscle weakness that worsens as the day progresses and improves after sleep. May have positive family history.
*H&P: Autoantibodies against AChR, presents with muscle weakness that worsens as the day progresses and improves after sleep. May have positive family history.
*Dx: Look for ptosis that improves with ice pack test. Edrophonium test is positive. EMG shows unstable baseline between APs.
*Dx: Look for ptosis that improves with ice pack test. Edrophonium test is positive. EMG shows unstable baseline between APs.
*Tx: Pyridostigmine.
*Tx: 1st line Pyridostigmine. 2nd line steroids or immunomodulating meds (e.g. cyclosporine, azathioprine). Plasmapheresis or IVIG for myasthenia crisis. Thymectomy may reduce symptoms and exacerbations.
==Lambert Eaton Myasthenia==
==Lambert Eaton Myasthenia==