Diuretics
Revision as of 13:08, 30 April 2023 by Aesetholephews (talk | contribs)
| Class | Site of action | Examples | Na Reabsorption |
|---|---|---|---|
| Carbonic anhydrase inhibitors | Proximal convoluted tubule | Acetazolamide | 69% |
| Loop | Thick ascending limb of loop of Henle | Furosemide, Bumetanide | 20% |
| Thiazide | Distal convoluted tubule | Metolazone, Chlorthalidone, Chlorothiazide (diuril) | 3-8% |
| Potassium sparing | Collecting duct | Spironolactone, Amiloride | 2-3% |
Sequential nephron blockade involves choosing multiple diuretics with different sites of action, avoid blocking all four segments though.